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For instance, the DPP4 inhibitor ER319711 alleviated DSS-induced colitis in mice, as evidenced by reduced weight loss
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LA maintains the cellular antioxidant state indirectly through activating the NRF2 pathway, and the NRF2 pathway governs the expression of antioxidant genes (such as -glutamylcysteine synthetase (-GCL), NAD(P)H quinone oxidoreductase 1 (NQO-1), and superoxide dismutase (SOD)) for enhancing the cell's antioxidant capacity and anti-inflammatory response [34, 35]
J Am Acad Dermatol 34(2 Pt 1):229234